Yes it is possible to setup Dead Peer Detection (DPD) on the Cisco VPN client (Cisco software client for connecting to remote VPN gateway). Cisco VPN Client sends its R-U-THERE message to a peer if it has sent traffic to the peer, but hasn’t received response back within ten seconds. This basically means that R-U-THERE messages are not sent if the VPN session is completely idle or the peer responds in a timely manner.
If the peer doesn’t respond with the R-U-THERE-ACK the VPN Client starts retransmitting R-U-THERE messages every five seconds until “Peer response timeout” is reached. After that the peer is declared dead.